Study on the liquid medium of tubercle bacilli
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چکیده
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Pyruvic acid egg medium for tubercle bacilli.
Sputum culture for tubercle bacilli on a solid egg medium containing glycerol was compared with culture on a similar medium containing pyruvic acid and no glycerol. Tubercle bacilli from the sputum of five out of 99 patients grew on pyruvic acid medium but not on glycerol medium. The addition of pyruvic acid is therefore essential when an egg medium is used for the cultural diagnosis of tubercu...
متن کاملThe behaviour of mixtures of streptomycin-sensitive and -resistant tubercle bacilli in liquid medium sensitivity tests.
A method for testing the sensitivity to streptomycin of strains of Mycobacterium tuberculosis has been recommended by the Streptomycin in Tuberculosis Trials Committee of the Medical Research Council (1948a). The tests are carried out in a modified Tween 80-albumen liquid medium (Dubos and Davis, 1946) containing various concentrations of streptomycin. It seems probable that strains derived fro...
متن کاملComparison of solid and liquid medium sensitivity tests of tubercle bacilli to para-aminosalicylic acid.
In the treatment of tuberculosis para-aminosalicylic acid (P.A.S.) is now chiefly used in combination with streptomycin or isoniazid with the aim of preventing or delaying the emergence of drug-resistant strains of tubercle bacilli (Medical Research Council, 1950, 1953c). Such combined therapy is only effective in preventing drug resistance when the strains obtained before the start of treatmen...
متن کاملFactors Affecting the Growth of Tubercle Bacilli in Liquid Media
1. Certain water-soluble esters of long chain fatty acids (in particular of oleic acid) favor submerged and diffuse growth of mycobacteria throughout the depth of synthetic liquid media. 2. Esters of oleic acid increase considerably the amount of growth yielded by avian strains in synthetic media. 3. The addition of serum albumin to synthetic liquid media permits visible growth of minimal inocu...
متن کاملOn the nucleoproteins of avian tubercle bacilli.
The nucleic acids of tubercle bacilli have formed the subject of several studies, among which may be mentioned those by Ruppel (l), Levene (2), and Johnson and his associates (3-5). The work of Mensel and Heidelberger (6) on the fractionation of the proteins of the tubercle bacillus revealed the presence of several protein fractions, rich in phosphorus and in purines, which appeared to be nucle...
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ژورنال
عنوان ژورنال: Nippon Saikingaku Zasshi
سال: 1956
ISSN: 1882-4110,0021-4930
DOI: 10.3412/jsb.11.1083